1 Summary

Luo Han Guo ( Siraitia grosvenorii（swingle）C. Jeffrey ex Lu et Z.Y. zhang [momordica grosvenori swingle; Thladiantha grosvenerii(Swingle) C. Jeffrey]) is a unique economic & medicinal plant in China. It is native in the north of Guangxi province, it has been regarded as the formal medicine for more than 300 years, being used traditionally to eliminate fever and relieve cough. In clinic it can treat breath system and digestive system diseases such as hypertension, Tuberculosis and asthma. Recent research indicated that the triterpene component mogrosides is the main effective ingredients. In 1995 FDA approve mogrosides to be utilized in food circle. In 1996 China approve the mogrosides to be the sweetening reagent for its high saccharinity, low calorie，light-color and good water solubility and stability.
3 Chemistry
Luo Han Guo extract (Momordica Grosvenori P.E.) is mainly composed of triterpenoid mogrosides, amino acids and vitamin, etc.
Triterpenoid glycosides
The glycosides in Luo Han Guo mainly as triterpene glycosides，part of compounds of cucurbitane type, the collecting of saponins. It includes Mogrosides II, III, IV, V, VI, siamcroside I, 11-oxo-Mogroside and neomogroside, etc. Triterpenoid glycoside V in Luo Han Guo is the major composition for sweetener.
4 Function
Luo Han Guo and its extracts had anti-diabetic preventive activity. Guilin Natural Ingredients Inc.and Department of Food Scince and Technology had studied the efficacy of Siraitia Grosvenori powder (SGP) and its extracts (SGE) on blood glucose in normal and diabetic mice. The result is bellowed:
4.1 Compare the body weight’s variety before test to that after test
4.1.1 Effect of SGP and SGE on weight of normal mice
Table 1 Effect of SGP and SGE on weight of normal mice
Group Dose
(g/kg